microglycodb_gene_00149
| Gene Number | Cj1130c |
|---|---|
| Gene Name | pglK |
| UniProt ID | Q0P9C4 |
| NOTES - phase variation etc | Flips LLO from cytoplasm into the periplasm |
| Sugar/modification added | Flippase |
| Reviewed | true |
| Biosynthesis | N-glycan biosynthesis |
| Organism | Campylobacter jejuni |
functions
sequence
publications
reaction
Mediates the ATP-dependent translocation of the undecaprenylpyrophosphate-linked heptasaccharide intermediate across the cell membrane; this is an essential step during the N-linked protein glycosylation pathway. Transport across the membrane is effected via ATP-driven conformation changes. Most likely, only the polar and charged part of the glycolipid enter the substrate-binding cavity, and the lipid tail remains exposed to the membrane lipids during the transmembrane flipping process.